Trp53-KO
Nomenclature
B6.129-Trp53tm1Smoc
Cat. NO.
NM-KO-00011
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Trp53
Model Description
A neo cassette replaces exons 2-11,including the start codon,of Trp53 (transformation related protein 53).Null homozygotes show high, early-onset tumor incidence;some have persistent hyaloid vasculature and cataracts.
Research Application：Tumorigenesis，aging，antineoplastic drug evaluation etc
*Literature published using this strain should indicate: Trp53-KO mice (Cat. NO. NM-KO-00011) were purchased from Shanghai Model Organisms Center, Inc..
You may also like
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn more
Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
Learn more
